![C44H53FN7O8 guanosine, 5 ′ -O- [bis (4-metoxyphenyl) fenilmethyl] -2 ′ -deoxy-2 ′ - fluoro-n- (2-methyl-1-oxopropyl) -, 3 ′ - [2-cyanoethyl N, N-bis (1-methyl ethyl) phosphoramaidite] (ACI)](http://cdn.globalso.com/nvchem/style/global/img/demo/page_banner.jpg)
![C44H53FN7O8 guanosine, 5 ′ -O- [bis (4-metoxyphenyl) fenilmetil] -2 ′ -deoxy-2 ′ - fluworo-n- (2-methyl-1-oxopropyl) -, 3 ′ - [2-cyanoethyl N, N-bis (1-methyl ethyl) phosphoramaidite]](https://cdn.globalso.com/nvchem/C44H53FN7O8.png)
C44H53FN7O8 guanosine, 5 ′ -O- [bis (4-metoxyphenyl) fenilmethyl] -2 ′ -deoxy-2 ′ - fluoro-n- (2-methyl-1-oxopropyl) -, 3 ′ - [2-cyanoethyl N, N-bis (1-methyl ethyl) phosphoramaidite] (ACI)
Numru tar-Reġistru CAS
144089-97-4
| Propjetajiet fiżiċi ewlenin | Valur | Kundizzjoni |
| Piż molekulari | 857.91 | - |
| PKA (imbassar) | 9.16 ± 0.20 | L-iktar temp aċiduż: 25 ° C |
Tbissim kanoniku
N # CCCOP (OC1C (F) C (OC1COC (C = 2C = CC = CC2) (C3 = CC = C (OC) C = C3) C4 = CC = C (OC) C = C4) N5C = Nc = 6C (= O) N = C (NC (NC (NC (= O) C (C) C) NC65) N (c) C) C (C) C
Tbissim isomeriku
C (oc [c @@ h] 1 [c @@ h] (op (n (c (c) c) c (c) c) occc # n) [c @@ h] (f) [c @@ h] (o1) n2c3 = c (n = c2) c (= o) n = c (nc (c (c) c) = o) n3) (c4 = cc = c (oc) c = C4) (C5 = CC = C (OC) C = C5) C6 = CC = CC = C6
Inchi
Inchi = 1s / c44h53fn7o8p / c1-27 (2) 40 (53) 49-43-48-39-37 (41 (54) 50-43) 47-26-51 (39) 42-36 (45) 38 (60-61 (58-24-12-23-46) 5 (3) 4) 6) 35 (59-42) 25-57-44 (30-13-10-9-11-14-30,31-15-19-33 (55-7) 20-16-31) 32-17-21-34 (56-8) 22-18-32 / H9-11,13-22,26-29,35-36,36,38,42h, 12, 12 24-25H2,1-8H3, (H2,48,49,50,53,54) / T35-, 36-, 38-, 42-, 61? / M1 / S1
INCHI Key
KjfumxzzvyMQeu-aocjbpqjsa-n
1 Isem ieħor għal din is-sustanza
Guanosine, 5 ′ -O- [bis (4-metoxyphenyl) fenilmetil] -2 ′ -deoxy-2 ′ -fluoro-N- (2-methyl-1-oxopropyl) -, 3 ′ - [2-cyanoethyl bis (1-metil etil) phosphoramidite] (9CI)
Proprjetajiet disponibbli
Bijoloġiku
Kimika
Lipinski
Struttura relatata
| Proprjetà | Valur | Kundizzjoni | Sors |
| Fattur tal-bijokonċentrazzjoni | 298 | pH 1; Temp: 25 ° C. | (1) ACD |
| Fattur tal-bijokonċentrazzjoni | 6350 | pH 2; Temp: 25 ° C. | (1) ACD |
| Fattur tal-bijokonċentrazzjoni | 57800 | pH 3; Temp: 25 ° C. | (1) ACD |
| Fattur tal-bijokonċentrazzjoni | 1.76 x 105 | pH 4; Temp: 25 ° C. | (1) ACD |
| Fattur tal-bijokonċentrazzjoni | 2.21 x 105 | pH 5; Temp: 25 ° C. | (1) ACD |
| Fattur tal-bijokonċentrazzjoni | 2.26 x 105 | pH 6; Temp: 25 ° C. | (1) ACD |
| Fattur tal-bijokonċentrazzjoni | 2.24 x 105 | pH 7; Temp: 25 ° C. | (1) ACD |
| Fattur tal-bijokonċentrazzjoni | 2.03 x 105 | pH 8; Temp: 25 ° C. | (1) ACD |
| Fattur tal-bijokonċentrazzjoni | 1.04 x 105 | pH 9; Temp: 25 ° C. | (1) ACD |
| Fattur tal-bijokonċentrazzjoni | 19300 | pH 10; Temp: 25 ° C. | (1) ACD |
(1) Ikkalkulat bl-użu ta 'Żvilupp tal-Kimika Avvanzata (ACD / Labs) Software V11.02 (© 1994-2023 ACD / Labs)
| Sors tal-Kundizzjoni tal-Valur tal-Propjetà |
| Koc 312 ph 1; Temp: 25 ° C (1) ACD |
| KOC 6630 ph 2; Temp: 25 ° C (1) ACD |
| KOC 60400 ph 3; Temp: 25 ° C (1) ACD |
| KOC 1.84 x 105 ph 4; Temp: 25 ° C (1) ACD |
| KOC 2.31 x 105 ph 5; Temp: 25 ° C (1) ACD |
| KOC 2.37 x 105 ph 6; Temp: 25 ° C (1) ACD |
| KOC 2.35 x 105 pH 7; Temp: 25 ° C (1) ACD |
| KOC 2.12 x 105 pH 8; Temp: 25 ° C (1) ACD |
| KOC 1.08 x 105 pH 9; Temp: 25 ° C (1) ACD |
| KOC 20200 PH 10; Temp: 25 ° C (1) ACD |
| LogD 4.47 pH 1; Temp: 25 ° C (1) ACD |
| LOGD 5.80 pH 2; Temp: 25 ° C (1) ACD |
| Proprjetà | Valur | Kundizzjoni | Sors |
| logd | 6.76 | pH 3; Temp: 25 ° C. | (1) ACD |
| logd | 7.24 | pH 4; Temp: 25 ° C. | (1) ACD |
| logd | 7.34 | pH 5; Temp: 25 ° C. | (1) ACD |
| logd | 7.35 | pH 6; Temp: 25 ° C. | (1) ACD |
| logd | 7.35 | pH 7; Temp: 25 ° C. | (1) ACD |
| logd | 7.30 | pH 8; Temp: 25 ° C. | (1) ACD |
| logd | 7.01 | pH 9; Temp: 25 ° C. | (1) ACD |
| logd | 6.28 | pH 10; Temp: 25 ° C. | (1) ACD |
| logp | 7.351 ± 0.713 | Temp: 25 ° C. | (1) ACD |
| Solubilità intrinsika tal-massa | 3.0 x 10-5 g / l | Temp: 25 ° C. | (1) ACD |
| Solubilità tal-Massa | 0.022 g / L. | pH 1; Temp: 25 ° C. | (1) ACD |
| Solubilità tal-Massa | 1.0 x 10-3 g / l | pH 2; Temp: 25 ° C. | (1) ACD |
| Solubilità tal-Massa | 1.2 x 10-4 g / l | pH 3; Temp: 25 ° C. | (1) ACD |
| Solubilità tal-Massa | 3.9 x 10-5 g / l | pH 4; Temp: 25 ° C. | (1) ACD |
| Solubilità tal-Massa | 3.1 x 10-5 g / l | pH 5; Temp: 25 ° C. | (1) ACD |
| Solubilità tal-Massa | 3.0 x 10-5 g / l | pH 6; Temp: 25 ° C. | (1) ACD |
| Solubilità tal-Massa | 3.0 x 10-5 g / l | pH 7; Temp: 25 ° C. | (1) ACD |
| Solubilità tal-Massa | 3.3 x 10-5 g / l | pH 8; Temp: 25 ° C. | (1) ACD |
| Solubilità tal-Massa | 6.5 x 10-5 g / l | pH 9; Temp: 25 ° C. | (1) ACD |
| Solubilità tal-Massa | 3.5 x 10-4 g / l | pH 10; Temp: 25 ° C. | (1) ACD |
| Solubilità tal-Massa | 3.0 x 10-5 g / l | PH tal-ilma mhux imballat 7.00; Temp: 25 ° C. | (1) ACD |
| Solubilità intrinsika molari | 3.5 x 10-8 mol / l | Temp: 25 ° C. | (1) ACD |
| Solubilità molari | 2.6 x 10-5 mol / l | pH 1; Temp: 25 ° C. | (1) ACD |
| Solubilità molari | 1.2 x 10-6 mol / l | pH 2; Temp: 25 ° C. | (1) ACD |
| Solubilità molari | 1.4 x 10-7 mol / l | pH 3; Temp: 25 ° C. | (1) ACD |
| Solubilità molari | 4.5 x 10-8 mol / l | pH 4; Temp: 25 ° C. | (1) ACD |
| Solubilità molari | 3.6 x 10-8 mol / l | pH 5; Temp: 25 ° C. | (1) ACD |
| Solubilità molari | 3.5 x 10-8 mol / l | pH 6; Temp: 25 ° C. | (1) ACD |
| Solubilità molari | 3.5 x 10-8 mol / l | pH 7; Temp: 25 ° C. | (1) ACD |
| Solubilità molari | 3.9 x 10-8 mol / l | pH 8; Temp: 25 ° C. | (1) ACD |
| Solubilità molari | 7.6 x 10-8 mol / l | pH 9; Temp: 25 ° C. | (1) ACD |
| Solubilità molari | 4.1 x 10-7 mol / l | pH 10; Temp: 25 ° C. | (1) ACD |
| Proprjetà | Valur | Kundizzjoni | Sors |
| Solubilità molari | 3.5 x 10-8 mol / l | PH tal-ilma mhux imballat 7.00; Temp: 25 ° C. | (1) ACD |
| Piż molekulari | 857.91 | ||
| PKA | 9.16 ± 0.20 | L-iktar temp aċiduż: 25 ° C | (1) ACD |
| PKA | 3.45 ± 0.70 | L-iktar temp bażiku: 25 ° C | (1) ACD |
(1) Ikkalkulat bl-użu ta 'Żvilupp tal-Kimika Avvanzata (ACD / Labs) Software V11.02 (© 1994-2023 ACD / Labs)
| Proprjetà | Valur | Sors tal-kundizzjoni |
| Erja tal-wiċċ polari | 184 A2 | (1) ACD |
(1) Ikkalkulat bl-użu ta 'Żvilupp tal-Kimika Avvanzata (ACD / Labs) Software V11.02 (© 1994-2023 ACD / Labs)
| Proprjetà | Valur | Kundizzjoni | Sors |
| Bonds li jduru liberament | 18 | (1) ACD | |
| H aċċettaturi | 15 | (1) ACD | |
| H donaturi | 2 | (1) ACD | |
| H Donatur / Aċċettatur Somma | 17 | (1) ACD | |
| logp | 7.351 ± 0.713 | Temp: 25 ° C. | (1) ACD |
| Piż molekulari | 857.91 |
(1) Ikkalkulat bl-użu ta 'Żvilupp tal-Kimika Avvanzata (ACD / Labs) Software V11.02 (© 1994-2023 ACD / Labs)
![C10H12N2O5 6H-FURO [2 ′, 3 ′: 4,5] oxazolo [3,2-a] pyrimidin-6-one, 2,3,3a, 9a-tetrah ydro-3-hydroxy-2- (hydroxymethyl) -7-methyl-, (2R, 3 r, 3AS, 9ar) - (9CI, ACI)](https://cdn.globalso.com/nvchem/C10H12N2O5-6H-Furo-300x300.jpg)
![C30H29FN2O7 uridine, 5′-O- [bis (4-metoxyphenyl) fenilmetil] -2′-deoxy-2′- fluoro- (9CI, ACI)](https://cdn.globalso.com/nvchem/C30H29FN2O7-Uridine-300x300.jpg)
